BIOCHEMISTRY - KSRCAS

Orcadian Population Investigating the Relationship between Human Plasma N-glycans and Metabolic Syndrome

Glycosylation refers to the enzymatic post-translational modification in which the addition of complex oligosaccharide molecules (glycans) enriches protein complexity and functional diversity. Glycans have a broad spectrum of biological roles, including their influence on protein folding, cell signaling and immune function. Alongside the genome and proteome, the human glycome is subject to immense variation.

Protein Markers Associated with an ALDH Sub-Population in Colorectal Cancer

Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. Although almost 70% of patients can be operated on with intent to cure, up to 30% of all these patients will relapse within 2-3 years. Survival rates for colon cancer have steadily improved mainly due to a combination of earlier diagnosis and improvements in treatment. Nevertheless, an improved understanding of the protein signaling pathways could provide new biomarkers for potential targets of therapeutic and surgical intervention.
By
Chandrasekaran
Final year biochemistry